产品货号：
Z27053
中文名称：
SMAD2/3抗体
英文名称：
Anti-SMAD2/3 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-SMAD2/3 Antibody |
| 指标别名 | SMAD family member 2;JV18;JV18-1;MADH2;MADR2;hMAD-2;hSMAD2;SMAD family member 3;HSPC193;HsT17436;JV15-2;LDS1C;LDS3;MADH3;SMAD2/3 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,IHC-F |
| 基因名称 | SMAD2/SMAD3 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the N-terminus of human SMAD2/3(32-47aa EQNGQEEKWCEKAVKS),identical to the related mouse and rat sequences. |
| 实际分子量 | 48KD,52KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | SMAD proteins transmit signals from transmembrane serine/threonine kinase receptors to the nucleus.Transforming growth factor(TGF)-beta stimulation leads to phosphorylation and activation of Smad2 and Smad3,which form complexes with Smad4 that accumulate in the nucleus and regulate transcription of target genes.Smad2 and Smad3 share highly homology.SMAD2/SMAD3 signal transduction appeared to be important in the regulation of muscle-specific genes.SMAD proteins transmit signals from transmembrane serine/threonine kinase receptors to the nucleus.Smad2 is a 58kDa member of a family of proteins involved in cell proliferation,differentiation and development.Smad3 is a 50kDa member of a family of proteins that act as key mediators of TGF beta superfamily signaling in cell proliferation,differentiation and development. |
| Uniprot ID | Q15796/P84022 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | SMAD family member 2/3 |
| 蛋白名全称 | Mothers against decapentaplegic homolog 2/3 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunohistochemistry in frozen section (IHC-F) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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